Global Clinical Head

At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality! If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person. 

We are hiring a Global Clinical Head in our Late Cardiovascular, Renal and Metabolism (CVRM) Global Development team.  This is a key role where you, with your strong leadership skills and drug development/ clinical trials experience, will impact and drive development programs in a dynamic global setting.  This role reports to the Vice President, Clinical Late CVRM and is based in Boston, MA. 

What you’ll do: 

The GCH is the most senior medical scientific authority on an asset team and is a core member of the Global Product Team (GPT). The GCH is accountable for all clinical and scientific aspects of the asset(s), including benefit/risk assessment, scientific strategies for clinical components of the Target Product Profile (TPP), Target Product Claim (TPC), Clinical Development Plan (CDP), and core labelling. The GCH develops the project strategy in partnership with the GPL/GPT. The GCH co-leads the Clinical Product Team (CPT) and has accountability for the clinical deliverables. 

Accountabilities include:

• Along with the Global Product Leader, provide scientific strategies for clinical components of the TPP, TPC, CDP, and core labelling 

• Accountable for the clinical parts of CPT deliverables 

• Responsible for overall clinical and scientific content for the asset 

• Work closely with the Clinical Operations lead and ensure the CPT rapidly implements new processes, systems and learning 

• Perform medical prioritization of clinical activities within the clinical program 

• Single-point accountable leader for the design, delivery and interpretation of clinical studies ensuring ethical and scientific integrity in compliance with AZ policies and Good Clinical Practice 

Basic Qualifications

• Graduate of a recognized school of medicine with an M.D. degree or MBBS, with 5+ years proven experience in drug development and/or significant Clinical Trials experience. 

• Demonstrated deep late-stage clinical and research expertise in cardiovascular, renal or metabolism disease 

• Delivered multiple complex and large studies (e.g., including but not limited to international outcome studies). 

• Demonstrated success in influencing global and local cross-functional stakeholders. 

• Experience assessing the benefit/risk profile of an asset and creating patient risk management plans. 

• Experience with global regulatory submissions and interacting with major regulatory agencies. 

The annual base salary for this position ranges from $323,216 - $484,824. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity and eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. 

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. 

Where can I find out more?

CVRM at AstraZeneca: https://www.astrazeneca.com/our-therapy-areas/cardiovascular-renal-and-metabolism.html

Life at AstraZeneca : https://careers.astrazeneca.com/inclusion-diversity

Date Posted

18-Dec-2025

Closing Date

01-Jan-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.